The Pathophysiological Hypothesis of Kidney Damage during Intra-Abdominal Hypertension
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چکیده
منابع مشابه
The Pathophysiological Hypothesis of Kidney Damage during Intra-Abdominal Hypertension
The increase in intra-abdominal pressure (IAP) above specific levels (i.e., intra-abdominal hypertension, IAH) may lead to organ dysfunction in abdominal and extra-abdominal systems (Kirkpatrick and Roberts, 2013). Possible etiologies or risk factors for IAH development comprehend diminished abdominal compliance, increased intraluminal or intra-abdominal contents and capillary leak/fluid resusc...
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The last several decades have seen many advances in the recognition and prevention of the abdominal compartment syndrome (ACS) and its precursor, intra-abdominal hypertension (IAH). There has also been a relative explosion of knowledge in the critical care, trauma, and surgical populations, and the inception of a society dedicated to its understanding, the World Society of the Abdominal Compart...
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The pressure within the abdominal cavity is normally little more than atmospheric pressure. However, even small increases in intra-abdominal pressure can have adverse effects on renal function, cardiac output, hepatic blood flow, respiratory mechanics, splanchnic perfusion and intracranial pressure. Although intra-abdominal pressure can be measured directly, this is invasive and bedside measure...
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A compartment syndrome exists when increased pressure in a closed anatomic space threatens the viability of the tissue within the compartment. When this occurs in the abdominal cavity it threatens not only the function of the intra-abdominal organs, but it can have a devastating effect on distant organs as well. Recent animal and human data suggest that the adverse effects of elevated intra-abd...
متن کاملHepatorenal syndrome: insights into the mechanisms of intra-abdominal hypertension.
OBJECTIVE Hepatorenal syndrome is one of the serious complications of cirrhosis and closely associated with the increasing intra-abdominal pressure (IAP). The study aims to explore the potential mechanism of intra-abdominal hypertension in the development of hepatorenal syndrome in mouse models. METHODS Eighty male mice were randomly divided into model group (subcutaneous injection of carbon ...
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ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2016
ISSN: 1664-042X
DOI: 10.3389/fphys.2016.00055